Ingredient Intelligence A–Z · Vitamin (B3)
Niacinamide
Also called: Vitamin B3, Nicotinamide
Editorial draft, pending expert review.Grades here are provisional editorial calls and may change after review. This is not medical advice.
What it is
The amide form of vitamin B3, widely used in leave-on skincare at low single-digit percentages.
Why it is trending
An established multi-purpose staple rather than a new trend. Trend signals to be updated with current data.
How it could work (mechanism only)
A precursor of NAD+, involved in cellular energy metabolism. In skin it is thought to support barrier lipid production and to reduce sebum and pigment transfer.
What human studies show
Randomised trials of topical niacinamide report modest, gradual improvements in barrier function, oiliness, uneven pigmentation and the look of fine lines. Oral nicotinamide has separate evidence in people at high risk of non-melanoma skin cancer; that is a different use and route from a cream.
Who may benefit
Oily, blemish-prone or unevenly toned skin, and people who want a well-tolerated all-rounder.
Safety
Generally well tolerated. Flushing or irritation is possible at higher concentrations or in sensitive skin.
Pregnancy and breastfeeding
Generally regarded as low-risk in topical form; confirm with your doctor if you are pregnant.
What regulators say
Widely permitted cosmetic ingredient. Oral nicotinamide is a separate supplement or medicine matter.
Where marketing overreaches
'Shrinks pores': pores can look smaller as oil falls, but pore size is largely genetic.
Independent editorial information only. It does not replace diagnosis, treatment or advice from your own doctor.